Active-Italia: TPF (total polyphenolic fraction) 100MG in eutectic, 10 mL vial (Oleocanthal, Oleacein, Tyrosol, Hydroxytyrosol) Oleatpeu

TPF (total polyphenolic fraction) 100MG in eutectic, 10 mL vial (Oleocanthal, Oleacein, Tyrosol, Hydroxytyrosol) Oleatpeu

110,00 ex. VAT

Total Phenolic Fraction (TPF)  from Olea Europaea, 100MG in eutectic, 10mL vial, Oleatpeu.
The TPF, standardized and characterized by an Oleacein and Oleocanthal content higher than 50% compared to the total polyphenols, has an Oleacein/Oleocanthal ratio of 50% ±10%, dissolved in NaDES solvent (Betaine:Propylene glycol) which gives high stability.
Reference Substance (For Research Use – Basic or discovery research in university labs or in life science industry labs).

134 in stock

TPF (total polyphenolic fraction) 100MG in eutectic, 10 mL vial (Oleocanthal, Oleacein, Tyrosol, Hydroxytyrosol) Oleatpeu

SKU tpf-eu-mixture-005 Categories , Tag

Description

Oleocanthal is a naturally occurring secoiridoid from olive oil, which was shown to exhibit potent anti-inflammatory, anticancer, and neuroprotective activities. The anti-inflammatory activity of oleocanthal is due to its dose dependent inhibition of cyclooxygenase (COX-1, COX-2) enzymes in the prostaglandin biosynthesis (inflammatory) in the same pathway as Ibuprofen. Anti-leishmanial activity was recently attributed to Oleocanthal when added in vitro and in vivo, in experimental models of Leishmania infection.

Oleacein is the main responsible of the positive effects of olive oil on cardiovascular system. Oleacein results, also, to be an inhibitor of MTOR pathway, an important methabolism and cellular growth regulation mechanism. Oleacein in vitro tests showed antinflammatory, antiatherosclerotic and antihypertensive properties, this last one by the inihibition of the angiotensin conversion enzyme, moreover, Oleacein is an inhibitor of the mammalian/mechanistic target of rapamycin (mTOR), an important metabolism and cellular growth regulation mechanism related to lifespan and aging.

The TPF improves redox status by increasing levels of GSH, one of the most important antioxidant molecules, in both endothelial cells and myoblasts.

CAS Numbers: Oleocanthal 289030-99-5; Oleacein 149183-75-5

Molecular Weight: OLEA 304.34 OLEO 320.34

Product certification or product qualification provided by Active Italia with every shipment.

Additional information

Weight0,900 kg
Dimensions30 × 20 × 20 mm
General description

This substance is supplied with certified chromatographic purity. The exact value can be found on the certificate. Produced by Sinthesys S.r.l. Roma IT

Availability

Estimated to ship on December 6, 2021

Active-Italia

PRODUCT INFORMATION

Product certification or product qualification provided by Active Italia with every shipment.

This substance is supplied with certified chromatographic purity.
Research Use Only.
Not For Human or Veterinary Use.

Certificate of Origin (COO)

Certificate of Origin provided by Active Italia with every shipment

Certificate of Origin (COO) Request

Please refer to your product packaging for the SKU and associated Lot Number; and type exactly as shown, including hyphens (-) and/or alphanumeric characters.

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